Playing with a strong wind at their backs, Acle got off to a dream start with Ian Morgan heading home within three minutes of the start.
Sam Whiting doubled the lead on 12 minutes, before Daniel Foreman hit a third just after 33 minutes, to give Acle a 3-0 lead at the break.
Dersingham pulled a goal back with 13 minutes remaining, but Aaron Sanders secured the points and top spot for Acle, with 3 minutes of normal time left in the game.
The Reserves slipped to a second successive defeat after losing 2-1 away to East Harling.
Match reports to follow................