It is the first time the Wirral based club have played in the UniBond League at Harrison Park and Blues will be seeking revenge for a 2-0 defeat at Kirklands back in November.
Lairds are currently 11th in the table nine points behind the Blues. On their travels they have won five, drawn four and lost seven of their sixteen matches.
Their recent form has been mixed, having won their last two games against Lincoln United and Rushall Olympic after a run of three consecutive defeats.
Leek have lost only twice in the last thirteen league games and remain unbeaten at home all season. Although eight in the league we are only two points off a fifth spot - the last play off position.
Blues boss Wayne Johnson will check on the fitness of defenders Pete Johnson and Andy Taylor before naming his side for the game.