Blues need to get back on track following the 5-2 hammering at Kidsgrove Athletic on Tuesday but could hardly have picked a more difficult fixture to do it in.
Sheffield FC are currently seven points behind leaders Mickleover Sports with a game in hand and they have taken the full fifteen points from their last five games.
Their home record is equally impressive, having won twelve and drawn one of their fourteen games at the BT Local Business Stadium. Their only defeat did come in spectacular style, Belper Town winning there 6-2 in early December.
Leek's away form is more mixed with six wins, two draws and six defeats from fourteen matches.
However Blues can take heart from the fact that in the three previous meetings between the clubs they have yet to be on the losing side.
There have been two draws at Harrison Park and Leon Ashman's late goal gave Leek a memorable 2-1 win at Sheffield last season.
As usual there will be live score updates on this site and text updates via twitter which can be accesed through the 'About Us' section and clicking on the 'links' tab.