The league will contain clubs that have been promoted but the three sides relegated from National 3 have all gone to the East league.
Matson return to the division after winning Western Counties North at a canter and join newcomers Okehampton (winners of Western Counties West) plus Kingsbridge ( Western Counties play-off winner) and Midsomer Norton (Southern Counties play-off winner).
The full list is:
Bideford
Bridgwater & Albion
Chard
Clevedon
Drybrook
Kingsbridge
Matson
Midsomer Norton
Newent
North Petherton
Okehampton
Teignmouth
Thornbury
Weston-super-Mare
The fixtures are due out by the end of the month.