The Fenmen completed a double over the Poachers with this Freeways Park success.
Sam Murphy boosted the visitors with a third minute opener, and Billy Smith added a 22nd minute second for the Fenmen.
Harry Allcock reduced the arrears seven minutes before the break, but the two goal Wisbech margin was restored by new man Alex Beck five minutes into the second half.
Again Oadby fought back through top scorer Sam Burton after 78 minutes, but their fate was sealed by Smith's second goal of the afternoon in the second added minute.
Oadby Town: Harry Allcock (38), Sam Burton (78)
Wisbech Town: Sam Murphy (3), Billy Smith (22,90+2), Alex Beck (50)
Report originally featured on theucl.co.uk Visit the site for more reports, latest news and fixtures from the United Counties League.