Town entered the Lancashire Senior Cup in their first four seasons, on each occasion having to play in the qualifying rounds. In 1901/02, Earlestown were beaten 2-0, before an epic battle with Wigan United, the tie going to two replays before Town won 3-2. This earned a long trip to Barrow in the First Round Proper, but Town lost 6-1. In 1902/03, there were two draws against Rochdale Town before St. Helens Town scratched, conceding the tie to their opponents. The following season, there were wins over Heywood (3-2), Bacup (5-0) and Bolton Wanderers (1-0 in a replay) before Town went out 1-0 at Southport Central. In 1904/05, Colne were beaten 2-0, but then Town were defeated 2-0 at Earlestown.

After an absence from the Lancashire Senior Cup for four seasons, Town resumed involvement in 1909/10, but whilst neighbours Recs. were to reach the Semi-Final at Everton, Town went out 4-1 at Southport Central in the First Round. Their next foray in this competition was in 1911/12. A home win over Chorley (3-1) was followed by a 7-0 thumping at Burnley. A 5-1 First Round exit at Barrow in 1912/13 (erroneously referred to as a pre-season friendly by me in last Tuesdays article) was followed by a longer run in 1913/14 when, after accounting for Haslingden 5-2 and Everton 1-0, a heavy 6-0 loss at Blackpool marked Towns last ever game in the Senior Cup.